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Mechanoluminescent materials

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NEW: Trap-controlled mechanoluminescent materials

Research Interests

 

Probes and sensors

Smart biomaterials

 

Drug delivery systems

 

Microscopy and in vivo imaging

 

Wearable devices

ICEA and ELICEA

New ImmunoAssay Platforms for at-home Diagnostics

 

New microscope techniques

Optical lock-in Detection microscopy

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PROTEIN STRUCTURE AND DYNAMICS

OLID-FRET

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Engineering human platelets

and exosomes as living therapeutics

Genetically-encoded sensors of macromolecule size and shape

New microscope techniques

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OLID and OLID-FRET

Optical switches and actuators

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Protein structure and dynamics

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KabC probes: imaging actin barbed ends

               FRET analysis of muscle contraction

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Actin-drug complexes

Mechanoluminescent materials

 
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Engineering Human Platelets and exosomes for tumour-target in vivo imaging and drug delivery

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Genetically-encoded sensors of macromolecule size and shape

Microscopy techniques and Sensors

olid-image.jpg

Genetically-encoded sensors for quantitative imaging of protein hydrodynamics, FLIM and  and FRET

OLID and OLID-FRET

wu-plos-one.png

Optical Lock-in Detection imaging Microscopy

Optical switches and actuators

Kabiramide probes:

imaging actin barbed ends

Protein structure and dynamics

               FRET analysis of muscle contraction

tropinin-fret.png
actin-gc04.jpg

Smart biomaterials and drug delivery vehicles

platelet.png

Engineering Human Platelets and exosomes for tumour-target in vivo imaging and drug delivery

Microscopy Techniques and Optical Sensors

Genetically-encoded sensors for quantitative imaging of protein hydrodynamics, FLIM and  and FRET

Kabiramide probes:

imaging actin barbed ends

Optical Lock-in Detection imaging Microscopy

olid-image.jpg

Optical switches and actuators

wu-plos-one.png

Protein structure and dynamics

tropinin-fret.png

Multi-FRET analysis of Tropomyosin Dynamics in Thin Filaments

actin-gc04.jpg

Actin-drug complexes